ABSTRACT
Abstract Purpose To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria. Methods Forty-two 5-mm diameter CSDs were made bilaterally in the calvaria of 18 rats. The animals were allocated according to the type of biomaterial and associations used to fill the CSD. After 8 weeks, the animals were euthanized, and their calvaria were evaluated for repaired tissue composition using histologic and histometric analyses. Results In the histometric analysis, the use of SVT showed to increase bone formation in the CSDs when combined with all the bone substitutes tested in this study (p<0.05). Greater bone formation was observed in the groups with SVT compared to the groups without SVT. Conclusions The use of SVT without the need for a vehicle and combined with a commercially available biomaterial may be a cheaper way to potentiate the formation of bone tissue without the need to produce new biomaterials. Therefore, SVT combined with DBB induced significantly greater new bone formation than did the other treatments.
Subject(s)
Humans , Animals , Female , Cattle , Rats , Osteogenesis/drug effects , Skull/drug effects , Biocompatible Materials/pharmacology , Collagen/pharmacology , Bone Substitutes/pharmacology , Simvastatin/pharmacology , Skull/surgery , Bone Regeneration/drug effects , Bone Transplantation/methods , Rats, Wistar , Disease Models, Animal , Anticholesteremic Agents/pharmacologyABSTRACT
INTRODUÇÃO: A Doença Periodontal é caracterizada por uma doença infecciosa resultante da inflamação dos tecidos de suporte e do tecido de revestimento dos dentes. Esta pode ser classificada em: gengivite quando compromete o periodonto de proteção e periodontite que acomete os tecidos de inserção. OBJETIVO: Este estudo teve como objetivo verificar o perfil periodontal dos pacientes atendidos na Faculdade de Odontologia da UniEVANGÉLICA, Anápolis- GO. MATERIAL E MÉTODO: Esta pesquisa documental descritiva retrospectiva avaliou prontuários de pacientes atendidos na clínica da Faculdade de Odontologia da UniEVANGÉLICA no período de 2009 a 2014. Nos prontuários foram analisados principalmente o Registro Periodontal Simplificado (PSR), a classificação da doença periodontal e o periograma dos pacientes que apresentaram periodontite. RESULTADOS: Dentre os 233 prontuários, 68% (n = 158) eram mulheres, 33,05% (n = 77) tinham entre 40 e 50 anos e 21% (n = 51) eram fumantes. Destes, 55 % (n = 129) possuíam gengivite e 45% (n=104) periodontite. Dos pacientes com periodontite, a Crônica Localizada foi constatada em 48% (n = 50), a Crônica Generalizada em 40% (n = 42), enquanto as Agressivas Localizada e Generalizada foram encontradas em 7% (n = 7) e 5% (n = 5) respectivamente. Pelos dados do PSR, pode-se observar que 49% (n = 114) apresentaram o código asterisco. CONCLUSÃO: De acordo com os resultados obtidos nesta pesquisa, pode-se notar uma prevalência de pacientes do gênero feminino e a gengivite foi a doença periodontal mais prevalente seguida pela periodontite crônica localizada.
INTRODUCTION: The Periodontal Disease is characterized by an infectious disease resulted from the inflammation of covering tissues (gingivitis) and/or of the support tissue (periodontitis) of teeth. OBJECTIVE: The objective of this study was to verify the periodontal profile of the patients attended at UniEVANGÉLICAS Dental School. MATERIAL AND METHOD: This is a descriptive documental and retrospective research that evaluated the records of the patients that were attended at UniEvangélicas Dental School clinic from 2009 to 2014. The Periodontal Screening and Record (PSR), the periodontal diseases classification and the periodontal chart of the patients that presented periodontitis were the main analysis performed from the records. RESULTS: Among the 233 records, 68% (n=158) were women, 33,05% (n=77) among 40 to 50 years old and 21% (n=51) were smokers. Among these, 55% (n=129) presented gingivitis, from the patients with periodontitis, 48% (n=50) were diagnosed with the Localized Chronic periodontitis, 40% (n=42) with the Generalized Chronic, while 7% (n=7) and 5% (n=5) had the Aggressive Localized and the Generalized Periodontitis, respectively. Through the PSR data, it was noticed that 49% (n=114) presented the asterisk code. CONCLUSION: According to the results of this research, a female prevalence could be noticed and the gingivitis was the most prevalent periodontal disease, followed by the Localized Chronic Periodontitis
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Gingivitis , Periodontitis , Prevalence , Medical Records Department, HospitalABSTRACT
Este relato de caso clínico demonstra a importância da interdisciplinaridade na prática clínica da Odontologia. Para tanto, foi descrito o caso de uma paciente que sofreu um traumatismo bucal, levando a fratura longitudinal no terço coronal radicular do incisivo central superior direito aos seis anos de idade. Foram descritos os procedimentos de tratamento endodôntico, exodontia do dente atingido, tratamento ortodôntico, colocação de enxerto ósseo autógeno no local, implante osseointegrável e, por fim, a colocação de prótese sobreimplante. O acompanhamento, por um longo período, deste caso clínico permitiu a verificação de que o maior sucesso na resolução de casos complexos é alcançado quando existe boa integração de uma equipe interdisciplinar em Odontologia.
The aim of this case report was to demonstrate the importance of the interdisciplinary in Dentistry clinical practice. It was described an oral trauma leading to a longitudinal root fracture on the right upper central incisor in a six years old patient. The procedures endodontics treatment, tooth extraction, orthodontics treatment, the fixation of autogenous bone graft and an implant, and then the installation of the prosthesis were performed. The patient was accompaniment for a long period (1 7 years) and the treatment showed that success in the resolution o/ complex cases is reached when a dentistry team works together.